Notes from Practice

Ketamine can reduce suicidal thoughts within hours, but its effects often fade within days. A new study suggests that adding low-dose buprenorphine may help extend ketamine’s life-saving benefits, offering a promising new approach to treating suicidal depression.

A Significant Moment for Psychedelic Medicine. Here's What You Need to Know Last week, President Trump signed an executive order directing federal agencies to speed up research and access to psychedelic drugs for serious mental illness. Yesterday, the FDA moved quickly on that directive, issuing fast-track review status to three treatments: psilocybin for hard-to-treat depression and methylone (a compound similar to MDMA) for PTSD. The FDA also approved the first-ever US clin

Since the sentencing last week, I have heard from patients who are frightened and reconsidering treatment. Matthew Perry died because of ketamine. What is also true is that what happened to him bore no resemblance to responsible clinical care, and that distinction matters enormously for patients considering this therapy today.

Integrative psychiatry is not a rejection of medication. It is a fuller way of thinking about mental health. Jamie Solomon, PMHNP-BC, explains how she thinks about baselines, biology, therapy, supplements, and what actually happens at a first appointment.

Psychedelic-assisted therapies are getting a lot of attention lately. From news headlines to podcasts, people are curious: could these...