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Notes from Practice
Writing on psychiatry, mental health, and the questions worth asking
This blog is for informational purposes only and reflects my own clinical perspective — not a substitute for professional medical advice. Please consult a qualified provider for questions about your care.


The First Few Weeks on an SSRI: What to Expect
Side effects usually show up before an SSRI starts helping. What the first few weeks really look like, how soon it starts working, and which early symptoms mean you should call your prescriber.
Jamie Solomon
1 day ago6 min read


Is GeneSight Testing Worth It? What Genetic Testing Can and Can't Tell You
A genetic test can show how your body processes certain psychiatric medications. It can't tell you which one will work. What GeneSight-style testing actually measures, how to read the red and green results, and when it's worth doing.
Jamie Solomon, PMHNP | Viewpoint
Oct 285 min read


What Your Family Taught You About Mental Health Before You Ever Needed Help
You can believe in therapy and understand that psychiatric medication is legitimate treatment, and still feel ashamed when you're the one who needs it. Often that discomfort comes from what your family taught you about mental health long before you had an opinion of your own.
Jamie Solomon, PMHNP | Viewpoint
Oct 167 min read


Getting a Head Start on Winter: Understanding Seasonal Depression
Fall officially started last week, and if you live anywhere in the northern half of the country, you've probably already noticed it's getting dark earlier. Right now we're losing a couple of minutes of daylight every day. On November 1 the clocks fall back, and suddenly it's dark by 5. This is the time of year I start bringing up seasonal depression with patients who've had it before. Not in December, when they're already sleeping ten hours and can't get off the couch. Now, w
Jamie Solomon
Oct 27 min read


Burnout or Anxiety? Why High-Functioning Professionals Often Have Both
Exhaustion, dread, and a brain that won't shut off can point to burnout, anxiety, or both. How the two differ in high-functioning professionals, and the question I ask first: what were you like before this job?
Jamie Solomon
Sep 212 min read


Antidepressants With the Least Sexual Side Effects: A Practical Guide
Sexual side effects are one of the most common reasons people stop antidepressants, and one of the least discussed. Here's why they happen, which antidepressants tend to be easier on sexual function, and what your options are if you're already dealing with them.
Jamie Solomon
Aug 197 min read


The Lindsey Clancy Case: What We Still Get Wrong About Postpartum Psychosis
The Lindsey Clancy case is almost impossible to talk about without having an emotional reaction. Three young children died. Their mother is accused of killing them. Their father lost his entire family in a matter of minutes. There is no version of this story that is not devastating. As a psychiatric provider, there is another part of this case that I keep coming back to: how poorly postpartum psychosis is understood. I have watched people point to details of Lindsey Clancy's
Jamie Solomon
Aug 136 min read


Auvelity: The Oral Antidepressant That Works More Like Ketamine
Whether Auvelity is right for you is a conversation to have with your prescriber. If you are reading this, chances are Auvelity has come up somewhere in your life. Maybe a doctor mentioned it, maybe you saw an ad, or maybe you have already tried a few antidepressants and someone told you this one is different. I want to walk through what it actually is, in plain language, so you can have a more grounded conversation with whoever is helping you. Auvelity is a newer antidepress
Jamie Solomon, PMHNP | Viewpoint
Jul 206 min read


When Ketamine Wears Off: A New Way to Keep Suicidal Thoughts at Bay
Ketamine can reduce suicidal thoughts within hours, but its effects often fade within days. A new study suggests that adding low-dose buprenorphine may help extend ketamine’s life-saving benefits, offering a promising new approach to treating suicidal depression.
Jamie Solomon, PMHNP | Viewpoint
Jun 304 min read


What Matthew Perry's death can and cannot tell us about ketamine therapy
Since the sentencing last week, I have heard from patients who are frightened and reconsidering treatment. Matthew Perry died because of ketamine. What is also true is that what happened to him bore no resemblance to responsible clinical care, and that distinction matters enormously for patients considering this therapy today.
Jamie Solomon, PMHNP | Viewpoint
Apr 135 min read


What Integrative Psychiatry Actually Means
Integrative psychiatry is not a rejection of medication. It is a fuller way of thinking about mental health. Jamie Solomon, PMHNP-BC, explains how she thinks about baselines, biology, therapy, supplements, and what actually happens at a first appointment.
Jamie Solomon, PMHNP | Viewpoint
Mar 214 min read


Wellbutrin: What It Does, Who It Helps, and Why It's Different
Bupropion, sold under the brand name Wellbutrin, is one of the most interesting and frequently misunderstood medications in psychiatry. Patients hear "antidepressant" and assume it works like everything else they've tried. It doesn't. Understanding what makes bupropion different can help you have a much more informed conversation with your prescriber about whether it makes sense for you. How It Works: The Dopamine and Norepinephrine Story Most antidepressants work primarily o
Jamie Solomon, PMHNP | Viewpoint
Mar 173 min read


Psilocybin, MDMA, and Ketamine: What’s the Difference?
Psychedelic-assisted therapies are getting a lot of attention lately. From news headlines to podcasts, people are curious: could these...
Jamie Solomon, PMHNP | Viewpoint
Oct 1, 20253 min read


Mood, Focus, and Menopause: What Every Woman Should Know
Menopause is often talked about in terms of hot flashes and night sweats. But for many women, the biggest changes show up in mood,...
Jamie Solomon, PMHNP | Viewpoint
Aug 19, 20254 min read


When Anxiety Stops Being Helpful
Anxiety is one of the most common mental health struggles. According to the National Institute of Mental Health , nearly one in three...
Jamie Solomon, PMHNP | Viewpoint
Aug 12, 20254 min read


What to Expect at Your First Psychiatry Appointment
Walking into a first psychiatry appointment can feel intimidating. Many people worry they’ll be judged, labeled, or rushed into a...
Jamie Solomon, PMHNP | Viewpoint
Aug 4, 20253 min read
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